Treatment of thyrotoxicosis resistant to carbimazole with corticosteroids.

Resistant Thyrotoxicosis in a Patient with Graves Disease: A Case Report

Background. Conventional management of thyrotoxicosis includes antithyroid drugs, radioactive iodine, and surgery while adjunctive treatment includes beta-blockers, corticosteroids, inorganic iodide and iopanoic acid. Very rarely, patients may be resistant to these modalities and require additional management. Case Presentation. A 50-year-old lady presented with weight loss and palpitations dia...

Carbimazole--resistant thyrotoxicosis.

Effect of pretreatment with carbimazole in patients with thyrotoxicosis subsequently treated with radioactive iodine.

Preliminary treatment with carbimazole in a series of 181 patients with thyrotoxicosis selected for treatment with radioactive iodine did not make any significant difference to the subsequent response to (131)I therapy.

Amiodarone-induced thyrotoxicosis responding to oral steroid therapy.

Sir, Amiodarone-induced thyrotoxicosis is well known for being difficult to treat. Thionamide drugs often fail,' and if possible amiodarone should be stopped. Recently there has been much work and discussion on the use of thionamides combined with potassium perchlorate, and the use of corticosteroids in the treatment of this condition. A 49 year old man presented to clinic having lost 2 stones ...

Two cases of amiodarone-induced thyrotoxicosis successfully treated with a short course of antithyroid drugs while amiodarone was continued.

Two patients with amiodarone-induced thyrotoxicosis were treated successfully with potassium perchlorate and carbimazole while treatment with amiodarone was continued. These antithyroid drugs were stopped after the patients had became clinically and biochemically euthyroid. During follow up, when treatment with amiodarone continued, thyrotoxicosis did not recur. Amiodarone-induced thyrotoxicosi...